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Changes in Antigen-specific IgG1 Fc N-glycosylation Upon Influenza and Tetanus Vaccination

Antibody effector functions have been shown to be influenced by the structure of the Fc N-glycans. Here we studied the changes in plasma or serum IgG Fc N-glycosylation upon vaccination of 10 Caucasian adults and 10 African children. Serum/plasma IgG was purified by affinity chromatography prior to...

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Detalles Bibliográficos
Autores principales: Selman, Maurice H. J., de Jong, Sanne E., Soonawala, Darius, Kroon, Frank P., Adegnika, Ayola Akim, Deelder, André M., Hokke, Cornelis H., Yazdanbakhsh, Maria, Wuhrer, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322571/
https://www.ncbi.nlm.nih.gov/pubmed/22184099
http://dx.doi.org/10.1074/mcp.M111.014563