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Challenges and surprises that arise with nucleic acids during model building and refinement

The process of building and refining crystal structures of nucleic acids, although similar to that for proteins, has some peculiarities that give rise to both various complications and various benefits. Although conventional isomorphous replacement phasing techniques are typically used to generate a...

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Detalles Bibliográficos
Autor principal: Scott, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322603/
https://www.ncbi.nlm.nih.gov/pubmed/22505264
http://dx.doi.org/10.1107/S0907444912001084