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Metabolomic Profiling of Fatty Acid and Amino Acid Metabolism in Youth With Obesity and Type 2 Diabetes: Evidence for enhanced mitochondrial oxidation

OBJECTIVE: We compared acylcarnitine (AcylCN) species, common amino acid and fat oxidation (FOX) byproducts, and plasma amino acids in normal weight (NW; n = 39), obese (OB; n = 64), and type 2 diabetic (n = 17) adolescents. RESEARCH DESIGN AND METHODS: Fasting plasma was analyzed by tandem mass spe...

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Detalles Bibliográficos
Autores principales: Mihalik, Stephanie J., Michaliszyn, Sara F., de las Heras, Javier, Bacha, Fida, Lee, SoJung, Chace, Donald H., DeJesus, Victor R., Vockley, Jerry, Arslanian, Silva A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322714/
https://www.ncbi.nlm.nih.gov/pubmed/22266733
http://dx.doi.org/10.2337/DC11-1577