LytA, Major Autolysin of Streptococcus pneumoniae, Requires Access to Nascent Peptidoglycan

The pneumococcal autolysin LytA is a virulence factor involved in autolysis as well as in fratricidal- and penicillin-induced lysis. In this study, we used biochemical and molecular biological approaches to elucidate which factors control the cytoplasmic translocation and lytic activation of LytA. W...

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Detalles Bibliográficos
Autores principales: Mellroth, Peter, Daniels, Robert, Eberhardt, Alice, Rönnlund, Daniel, Blom, Hans, Widengren, Jerker, Normark, Staffan, Henriques-Normark, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322828/
https://www.ncbi.nlm.nih.gov/pubmed/22334685
http://dx.doi.org/10.1074/jbc.M111.318584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322828/
https://www.ncbi.nlm.nih.gov/pubmed/22334685
http://dx.doi.org/10.1074/jbc.M111.318584

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