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LytA, Major Autolysin of Streptococcus pneumoniae, Requires Access to Nascent Peptidoglycan

The pneumococcal autolysin LytA is a virulence factor involved in autolysis as well as in fratricidal- and penicillin-induced lysis. In this study, we used biochemical and molecular biological approaches to elucidate which factors control the cytoplasmic translocation and lytic activation of LytA. W...

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Detalles Bibliográficos
Autores principales:	Mellroth, Peter, Daniels, Robert, Eberhardt, Alice, Rönnlund, Daniel, Blom, Hans, Widengren, Jerker, Normark, Staffan, Henriques-Normark, Birgitta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322828/ https://www.ncbi.nlm.nih.gov/pubmed/22334685 http://dx.doi.org/10.1074/jbc.M111.318584

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