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Open-label feasibility study of pazopanib, carboplatin, and paclitaxel in women with newly diagnosed, untreated, gynaecologic tumours: a phase I/II trial of the AGO study group

INTRODUCTION: Although most patients with advanced gynaecologic malignancies respond to first-line treatment with platinum-taxane doublets, a significant proportion of patients relapse. Combining targeted agents that have non-overlapping mechanisms of action with chemotherapy may potentially increas...

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Detalles Bibliográficos
Autores principales: du Bois, A, Vergote, I, Wimberger, P, Ray-Coquard, I, Harter, P, Curtis, L B, Mitrica, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322958/
https://www.ncbi.nlm.nih.gov/pubmed/22240783
http://dx.doi.org/10.1038/bjc.2011.608