Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge

Apolipoprotein E (APOE)-ɛ4 is associated with a deleterious outcome after ischemic brain injury, which may involve abnormal regulation of mitochondrial function. We have assessed the mitochondrial proteomic response of APOE-ɛ3 and APOE-ɛ4 transgenic mice to transient global ischemic injury in the hi...

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Detalles Bibliográficos
Autores principales: James, Rachel, Searcy, James L, Le Bihan, Thierry, Martin, Sarah F, Gliddon, Catherine M, Povey, Joanne, Deighton, Ruth F, Kerr, Lorraine E, McCulloch, James, Horsburgh, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323298/
https://www.ncbi.nlm.nih.gov/pubmed/21878944
http://dx.doi.org/10.1038/jcbfm.2011.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323298/
https://www.ncbi.nlm.nih.gov/pubmed/21878944
http://dx.doi.org/10.1038/jcbfm.2011.120

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