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Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge
Apolipoprotein E (APOE)-ɛ4 is associated with a deleterious outcome after ischemic brain injury, which may involve abnormal regulation of mitochondrial function. We have assessed the mitochondrial proteomic response of APOE-ɛ3 and APOE-ɛ4 transgenic mice to transient global ischemic injury in the hi...
Autores principales: | James, Rachel, Searcy, James L, Le Bihan, Thierry, Martin, Sarah F, Gliddon, Catherine M, Povey, Joanne, Deighton, Ruth F, Kerr, Lorraine E, McCulloch, James, Horsburgh, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323298/ https://www.ncbi.nlm.nih.gov/pubmed/21878944 http://dx.doi.org/10.1038/jcbfm.2011.120 |
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