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Functional analysis of hepatitis B virus pre-s deletion variants associated with hepatocellular carcinoma

BACKGROUND: Naturally occurring pre-S deletion mutants have been identified in hepatitis B carriers and shown to be associated with the development of hepatocellular carcinoma. The phenotypes of these pre-S deletion genomes remain unclear, and they were investigated in this study. METHODS: The pre-S...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Ming, Wang, Gen-Ming, Jow, Guey-Mei, Chen, Bing-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323466/
https://www.ncbi.nlm.nih.gov/pubmed/22313590
http://dx.doi.org/10.1186/1423-0127-19-17