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Comparative study of (64)Cu/NOTA-[D-Tyr(6),βAla(11),Thi(13),Nle(14)]BBN(6-14) monomer and dimers for prostate cancer PET imaging

BACKGROUND: Gastrin-releasing peptide receptors [GRPR] are highly over-expressed in multiple cancers and have been studied as a diagnostic target. Multimeric gastrin-releasing peptides are expected to have enhanced tumor uptake and affinity for GRPR. In this study, a (64)Cu-labeled 1,4,7-triazacyclo...

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Detalles Bibliográficos
Autores principales: Fournier, Patrick, Dumulon-Perreault, Véronique, Ait-Mohand, Samia, Langlois, Réjean, Bénard, François, Lecomte, Roger, Guérin, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323469/
https://www.ncbi.nlm.nih.gov/pubmed/22333272
http://dx.doi.org/10.1186/2191-219X-2-8