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Identification of Critical Amino Acids in an Immunodominant IgE Epitope of Pen c 13, a Major Allergen from Penicillium citrinum

BACKGROUND: Pen c 13, identified as a 33-kDa alkaline serine protease, is a major allergen secreted by Penicillium citrinum. Detailed knowledge about the epitopes responsible for IgE binding would help inform the diagnosis/prognosis of fungal allergy and facilitate the rational design of hypoallerge...

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Detalles Bibliográficos
Autores principales: Chen, Jui-Chieh, Chiu, Li-Li, Lee, Kuang-Lun, Huang, Wei-Ning, Chuang, Jiing-Guang, Liao, Hsin-Kai, Chow, Lu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323554/
https://www.ncbi.nlm.nih.gov/pubmed/22506037
http://dx.doi.org/10.1371/journal.pone.0034627