Activation of Cell Cycle Arrest and Apoptosis by the Proto-Oncogene Pim-2

Potent survival effects have been ascribed to the serine/threonine kinase proto-oncogene PIM-2. Elevated levels of PIM-2 are associated with various malignancies. In human cells, a single Pim-2 transcript gives rise mainly to two protein isoforms (34, 41 kDa) that share an identical catalytic site b...

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Detalles Bibliográficos
Autores principales: Levy, Daphna, Davidovich, Ateret, Zirkin, Shahar, Frug, Yulia, Cohen, Amos M., Shalom, Sara, Don, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323563/
https://www.ncbi.nlm.nih.gov/pubmed/22506047
http://dx.doi.org/10.1371/journal.pone.0034736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323563/
https://www.ncbi.nlm.nih.gov/pubmed/22506047
http://dx.doi.org/10.1371/journal.pone.0034736

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