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Increased CD45RA(+)FoxP3(low) Regulatory T Cells with Impaired Suppressive Function in Patients with Systemic Lupus Erythematosus
BACKGROUND: The role of naturally occurring regulatory T cells (Treg) in the control of the development of systemic lupus erythematosus (SLE) has not been well defined. Therefore, we dissect the phenotypically heterogeneous CD4(+)FoxP3(+) T cells into subpopulations during the dynamic SLE developmen...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323568/ https://www.ncbi.nlm.nih.gov/pubmed/22506043 http://dx.doi.org/10.1371/journal.pone.0034662 |