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Increased CD45RA(+)FoxP3(low) Regulatory T Cells with Impaired Suppressive Function in Patients with Systemic Lupus Erythematosus

BACKGROUND: The role of naturally occurring regulatory T cells (Treg) in the control of the development of systemic lupus erythematosus (SLE) has not been well defined. Therefore, we dissect the phenotypically heterogeneous CD4(+)FoxP3(+) T cells into subpopulations during the dynamic SLE developmen...

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Detalles Bibliográficos
Autores principales: Pan, Xiujun, Yuan, Xiangliang, Zheng, Yingxia, Wang, Weiwei, Shan, Jianping, Lin, Fujun, Jiang, Gengru, Yang, Yuan H., Wang, Die, Xu, Dakang, Shen, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323568/
https://www.ncbi.nlm.nih.gov/pubmed/22506043
http://dx.doi.org/10.1371/journal.pone.0034662