A New Human NHERF1 Mutation Decreases Renal Phosphate Transporter NPT2a Expression by a PTH-Independent Mechanism

BACKGROUND: The sodium-hydrogen exchanger regulatory factor 1 (NHERF1) binds to the main renal phosphate transporter NPT2a and to the parathyroid hormone (PTH) receptor. We have recently identified mutations in NHERF1 that decrease renal phosphate reabsorption by increasing PTH-induced cAMP producti...

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Detalles Bibliográficos
Autores principales: Courbebaisse, Marie, Leroy, Christine, Bakouh, Naziha, Salaün, Christine, Beck, Laurent, Grandchamp, Bernard, Planelles, Gabrielle, Hall, Randy A., Friedlander, Gérard, Prié, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323571/
https://www.ncbi.nlm.nih.gov/pubmed/22506049
http://dx.doi.org/10.1371/journal.pone.0034764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323571/
https://www.ncbi.nlm.nih.gov/pubmed/22506049
http://dx.doi.org/10.1371/journal.pone.0034764

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