Cargando…

A New Human NHERF1 Mutation Decreases Renal Phosphate Transporter NPT2a Expression by a PTH-Independent Mechanism

BACKGROUND: The sodium-hydrogen exchanger regulatory factor 1 (NHERF1) binds to the main renal phosphate transporter NPT2a and to the parathyroid hormone (PTH) receptor. We have recently identified mutations in NHERF1 that decrease renal phosphate reabsorption by increasing PTH-induced cAMP producti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Courbebaisse, Marie, Leroy, Christine, Bakouh, Naziha, Salaün, Christine, Beck, Laurent, Grandchamp, Bernard, Planelles, Gabrielle, Hall, Randy A., Friedlander, Gérard, Prié, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323571/ https://www.ncbi.nlm.nih.gov/pubmed/22506049 http://dx.doi.org/10.1371/journal.pone.0034764

Ejemplares similares

Functional Interaction between CFTR and the Sodium-Phosphate Co-Transport Type 2a in Xenopus laevis Oocytes
por: Bakouh, Naziha, et al.
Publicado: (2012)

RGS14 regulates PTH- and FGF23-sensitive NPT2A-mediated renal phosphate uptake via binding to the NHERF1 scaffolding protein
por: Friedman, Peter A., et al.
Publicado: (2022)

Relationship between clinical phenotype and in vitro analysis of 13 NPT2c/SCL34A3 mutants
por: Brazier, François, et al.
Publicado: (2023)

Noncanonical Sequences Involving NHERF1 Interaction with NPT2A Govern Hormone-Regulated Phosphate Transport: Binding Outside the Box
por: Mamonova, Tatyana, et al.
Publicado: (2021)

The Phosphate Transporter PiT1 (Slc20a1) Revealed As a New Essential Gene for Mouse Liver Development
por: Beck, Laurent, et al.
Publicado: (2010)

Canonical and Noncanonical Sites Determine NPT2A Binding Selectivity to NHERF1 PDZ1
por: Mamonova, Tatyana, et al.
Publicado: (2015)

THU393 An Internal NPT2A Cryptic PDZ Motif Is A Novel Regulator of PTH- And FGF23-sensitive Phosphate Transport
por: Sneddon, Bruce W, et al.
Publicado: (2023)

In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
por: Louet, Maxime, et al.
Publicado: (2017)

Plasma Fibroblast Growth Factor 23 Concentration Is Increased and Predicts Mortality in Patients on the Liver-Transplant Waiting List
por: Prié, Dominique, et al.
Publicado: (2013)

NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex
por: Bushau-Sprinkle, Adrienne, et al.
Publicado: (2020)

Knockdown of the Sodium-Dependent Phosphate Co-Transporter 2b (NPT2b) Suppresses Lung Tumorigenesis
por: Hong, Seong-Ho, et al.
Publicado: (2013)

Correction: Knockdown of the Sodium-Dependent Phosphate Co-Transporter 2b (NPT2b) Suppresses Lung Tumorigenesis
por: Hong, Seong-Ho, et al.
Publicado: (2014)

Treaty on the non-proliferation of nuclear weapons (NPT)
por: International Atomic Energy Agency. Vienna
Publicado: (1968)

Unwrapping NPT Simulations to Calculate Diffusion Coefficients
por: Bullerjahn, Jakob Tómas, et al.
Publicado: (2023)

Roles for NHERF1 and NHERF2 on the Regulation of C3a Receptor Signaling in Human Mast Cells
por: Subramanian, Hariharan, et al.
Publicado: (2012)

Multisite NHERF1 phosphorylation controls GRK6A regulation of hormone-sensitive phosphate transport
por: Vistrup-Parry, Maria, et al.
Publicado: (2021)

Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models
por: Wang, Xiaojun, et al.
Publicado: (2022)

Molecular interactions of FGF23 and PTH in phosphate regulation
por: Lanske, Beate, et al.
Publicado: (2014)

Near-peer teaching (NPT): the importance of process evaluation
por: Reyes, Cynthia G., et al.
Publicado: (2014)

NPT-IIb Inhibition Does Not Improve Hyperphosphatemia in CKD
por: Larsson, Tobias E., et al.
Publicado: (2017)

Npt2a as a target for treating hyperphosphatemia
por: Thomas, Linto, et al.
Publicado: (2022)

Determination of the best method to estimate glomerular filtration rate from serum creatinine in adult patients with sickle cell disease: a prospective observational cohort study
por: Arlet, Jean-Benoît, et al.
Publicado: (2012)

Physiological regulation of phosphate by vitamin D, parathyroid hormone (PTH) and phosphate (Pi)
por: Jacquillet, Grégory, et al.
Publicado: (2018)

The Biological Relevance of NHERF1 Protein in Gynecological Tumors
por: Sonnessa, Margherita, et al.
Publicado: (2022)

The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2–ezrin binding and dexamethasone stimulated NHE3 activity
por: Yang, Jianbo, et al.
Publicado: (2015)

A variant of ASIC2 mediates sodium retention in nephrotic syndrome
por: Fila, Marc, et al.
Publicado: (2021)

Response of Npt2a knockout mice to dietary calcium and phosphorus
por: Li, Yuwen, et al.
Publicado: (2017)

NHERF2 is crucial in ERM phosphorylation in pulmonary endothelial cells
por: Boratkó, Anita, et al.
Publicado: (2013)

HPV16 Impacts NHERF2 Expression in Oropharyngeal Cancers
por: Lulić, Lucija, et al.
Publicado: (2023)

Renal Phosphate Handling: Independent Effects of Circulating FGF23, PTH, and Calcium
por: McKenna, Malachi J, et al.
Publicado: (2020)

NPT088 reduces both amyloid-β and tau pathologies in transgenic mice
por: Levenson, Jonathan M., et al.
Publicado: (2016)

Four Curious Cases of Closed-Incision Negative Pressure Therapy (ciNPT)
por: Huan, Sarah, et al.
Publicado: (2020)

Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT
por: Gardner, Eric D., et al.
Publicado: (2020)

Nuclear NHERF1 expression as a prognostic marker in breast cancer
por: Paradiso, A, et al.
Publicado: (2013)

NHERF1 Enhances Cisplatin Sensitivity in Human Cervical Cancer Cells
por: Tao, Tao, et al.
Publicado: (2017)

NHERF1 Between Promises and Hopes: Overview on Cancer and Prospective Openings()
por: Centonze, Matteo, et al.
Publicado: (2018)

CFTR-NHERF2-LPA(2) Complex in the Airway and Gut Epithelia
por: Zhang, Weiqiang, et al.
Publicado: (2017)

VITamin D supplementation in renAL transplant recipients (VITALE): a prospective, multicentre, double-blind, randomized trial of vitamin D estimating the benefit and safety of vitamin D(3) treatment at a dose of 100,000 UI compared with a dose of 12,000 UI in renal transplant recipients: study protocol for a double-blind, randomized, controlled trial
por: Courbebaisse, Marie, et al.
Publicado: (2014)

Serum iPTH, calcium and phosphate, and the risk of mortality in a European haemodialysis population
por: Floege, Jürgen, et al.
Publicado: (2011)

Intraperitoneal pyrophosphate treatment reduces renal calcifications in Npt2a null mice
por: Caballero, Daniel, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_16q7a2r5t9v0i7aju4qk0dgck4