Membrane Association of the PTEN Tumor Suppressor: Molecular Details of the Protein-Membrane Complex from SPR Binding Studies and Neutron Reflection

The structure and function of the PTEN phosphatase is investigated by studying its membrane affinity and localization on in-plane fluid, thermally disordered synthetic membrane models. The membrane association of the protein depends strongly on membrane composition, where phosphatidylserine (PS) and...

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Detalles Bibliográficos
Autores principales: Shenoy, Siddharth, Shekhar, Prabhanshu, Heinrich, Frank, Daou, Marie-Claire, Gericke, Arne, Ross, Alonzo H., Lösche, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323581/
https://www.ncbi.nlm.nih.gov/pubmed/22505997
http://dx.doi.org/10.1371/journal.pone.0032591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323581/
https://www.ncbi.nlm.nih.gov/pubmed/22505997
http://dx.doi.org/10.1371/journal.pone.0032591

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