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Caveolin-1-Enhanced Motility and Focal Adhesion Turnover Require Tyrosine-14 but Not Accumulation to the Rear in Metastatic Cancer Cells

Caveolin-1 is known to promote cell migration, and increased caveolin-1 expression is associated with tumor progression and metastasis. In fibroblasts, caveolin-1 polarization and phosphorylation of tyrosine-14 are essential to promote migration. However, the role of caveolin-1 in migration of metas...

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Detalles Bibliográficos
Autores principales: Urra, Hery, Torres, Vicente A., Ortiz, Rina J., Lobos, Lorena, Díaz, María I., Díaz, Natalia, Härtel, Steffen, Leyton, Lisette, Quest, Andrew F. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323582/
https://www.ncbi.nlm.nih.gov/pubmed/22505999
http://dx.doi.org/10.1371/journal.pone.0033085