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Optogenetic Mimicry of the Transient Activation of Dopamine Neurons by Natural Reward Is Sufficient for Operant Reinforcement

Activation of dopamine receptors in forebrain regions, for minutes or longer, is known to be sufficient for positive reinforcement of stimuli and actions. However, the firing rate of dopamine neurons is increased for only about 200 milliseconds following natural reward events that are better than ex...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Man, Baratta, Michael V., Yang, Aimei, Lee, Doheon, Boyden, Edward S., Fiorillo, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323614/
https://www.ncbi.nlm.nih.gov/pubmed/22506004
http://dx.doi.org/10.1371/journal.pone.0033612