The Immune Response to Melanoma Is Limited by Thymic Selection of Self-Antigens

The expression of melanoma-associated antigens (MAA) being limited to normal melanocytes and melanomas, MAAs are ideal targets for immunotherapy and melanoma vaccines. As MAAs are derived from self, immune responses to these may be limited by thymic tolerance. The extent to which self-tolerance prev...

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Detalles Bibliográficos
Autores principales: Träger, Ulrike, Sierro, Sophie, Djordjevic, Gordana, Bouzo, Basma, Khandwala, Shivani, Meloni, Antonella, Mortensen, Monika, Simon, Anna Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323626/
https://www.ncbi.nlm.nih.gov/pubmed/22506061
http://dx.doi.org/10.1371/journal.pone.0035005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323626/
https://www.ncbi.nlm.nih.gov/pubmed/22506061
http://dx.doi.org/10.1371/journal.pone.0035005

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