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Simultaneous Disruption of Mouse ASIC1a, ASIC2 and ASIC3 Genes Enhances Cutaneous Mechanosensitivity

Three observations have suggested that acid-sensing ion channels (ASICs) might be mammalian cutaneous mechanoreceptors; they are structurally related to Caenorhabditis elegans mechanoreceptors, they are localized in specialized cutaneous mechanosensory structures, and mechanical displacement generat...

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Detalles Bibliográficos
Autores principales: Kang, Sinyoung, Jang, Jun Ho, Price, Margaret P., Gautam, Mamta, Benson, Christopher J., Gong, Huiyu, Welsh, Michael J., Brennan, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323639/
https://www.ncbi.nlm.nih.gov/pubmed/22506072
http://dx.doi.org/10.1371/journal.pone.0035225