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Microtubular Stability Affects pVHL-Mediated Regulation of HIF-1alpha via the p38/MAPK Pathway in Hypoxic Cardiomyocytes

BACKGROUND: Our previous research found that structural changes of the microtubule network influence glycolysis in cardiomyocytes by regulating the hypoxia-inducible factor (HIF)-1α during the early stages of hypoxia. However, little is known about the underlying regulatory mechanism of the changes...

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Detalles Bibliográficos
Autores principales: Teng, Miao, Jiang, Xu-pin, Zhang, Qiong, Zhang, Jia-ping, Zhang, Dong-xia, Liang, Guang-ping, Huang, Yue-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323643/
https://www.ncbi.nlm.nih.gov/pubmed/22506063
http://dx.doi.org/10.1371/journal.pone.0035017