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A Sensitive Membrane-Targeted Biosensor for Monitoring Changes in Intracellular Chloride in Neuronal Processes

BACKGROUND: Regulation of chloride gradients is a major mechanism by which excitability is regulated in neurons. Disruption of these gradients is implicated in various diseases, including cystic fibrosis, neuropathic pain and epilepsy. Relatively few studies have addressed chloride regulation in neu...

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Detalles Bibliográficos
Autores principales: Watts, Spencer D., Suchland, Katherine L., Amara, Susan G., Ingram, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323644/
https://www.ncbi.nlm.nih.gov/pubmed/22506078
http://dx.doi.org/10.1371/journal.pone.0035373