Bacterial persistence increases as environmental fitness decreases

Since persister cells cause chronic infections and since Escherichia coli toxin MqsR increases persisters, we used protein engineering to increase the toxicity of MqsR to gain insights into persister cell formation. Through two amino acid replacements that increased the stability of MqsR, toxicity a...

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Detalles Bibliográficos
Autores principales: Hong, Seok Hoon, Wang, Xiaoxue, O'Connor, Hazel F., Benedik, Michael J., Wood, Thomas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323757/
https://www.ncbi.nlm.nih.gov/pubmed/22221537
http://dx.doi.org/10.1111/j.1751-7915.2011.00327.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323757/
https://www.ncbi.nlm.nih.gov/pubmed/22221537
http://dx.doi.org/10.1111/j.1751-7915.2011.00327.x

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