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Structural Basis for Acyl Acceptor Specificity in the Achromobactin Biosynthetic Enzyme AcsD

Siderophores are known virulence factors, and their biosynthesis is a target for new antibacterial agents. A non-ribosomal peptide synthetase-independent siderophore biosynthetic pathway in Dickeya dadantii is responsible for production of the siderophore achromobactin. The D. dadantii achromobactin...

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Detalles Bibliográficos
Autores principales: Schmelz, Stefan, Botting, Catherine H., Song, Lijiang, Kadi, Nadia F., Challis, Gregory L., Naismith, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323832/
https://www.ncbi.nlm.nih.gov/pubmed/21835184
http://dx.doi.org/10.1016/j.jmb.2011.07.059