Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways

INTRODUCTION: Platelet adhesion to collagen under high shear rates depends on the optimal size of the von Willebrand factor (VWF) multimers, which is determined by their limited proteolysis. The present study attempts to identify the role of hemostatic-fibrinolytic enzymes (thrombin, plasmin) and le...

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Detalles Bibliográficos
Autores principales: Wohner, Nikolett, Kovács, András, Machovich, Raymund, Kolev, Krasimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2012
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323834/
https://www.ncbi.nlm.nih.gov/pubmed/22178067
http://dx.doi.org/10.1016/j.thromres.2011.11.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323834/
https://www.ncbi.nlm.nih.gov/pubmed/22178067
http://dx.doi.org/10.1016/j.thromres.2011.11.021

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