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Sub-Regional Hippocampal Injury is Associated with Fornix Degeneration in Alzheimer’s Disease

We examined in vivo evidence of axonal degeneration in association with neuronal pathology in Alzheimer’s disease (AD) through analysis of fornix microstructural integrity and measures of hippocampal subfield atrophy. Based on known anatomical topography, we hypothesized that the local thickness of...

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Detalles Bibliográficos
Autores principales: Lee, Dong Young, Fletcher, Evan, Carmichael, Owen Thomas, Singh, Baljeet, Mungas, Dan, Reed, Bruce, Martinez, Oliver, Buonocore, Michael H., Persianinova, Maria, DeCarli, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323836/
https://www.ncbi.nlm.nih.gov/pubmed/22514534
http://dx.doi.org/10.3389/fnagi.2012.00001