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Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies

HIV-1's subtype C V3 loop consensus sequence exhibits increased resistance to anti-V3 antibody-mediated neutralization as compared to the subtype B consensus sequence. The dynamic 3D structure of the consensus C V3 loop crown, visualized by ab initio folding, suggested that the resistance deriv...

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Detalles Bibliográficos
Autores principales: Almond, David, Krachmarov, Chavdar, Swetnam, James, Zolla-Pazner, Susan, Cardozo, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323838/
https://www.ncbi.nlm.nih.gov/pubmed/22548061
http://dx.doi.org/10.1155/2012/803535