Cargando…
Resistance of Subtype C HIV-1 Strains to Anti-V3 Loop Antibodies
HIV-1's subtype C V3 loop consensus sequence exhibits increased resistance to anti-V3 antibody-mediated neutralization as compared to the subtype B consensus sequence. The dynamic 3D structure of the consensus C V3 loop crown, visualized by ab initio folding, suggested that the resistance deriv...
Autores principales: | Almond, David, Krachmarov, Chavdar, Swetnam, James, Zolla-Pazner, Susan, Cardozo, Timothy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323838/ https://www.ncbi.nlm.nih.gov/pubmed/22548061 http://dx.doi.org/10.1155/2012/803535 |
Ejemplares similares
-
Comparative Magnitude of Cross-Strain Conservation of HIV Variable Loop Neutralization Epitopes
por: Swetnam, James, et al.
Publicado: (2010) -
Focusing the immune response on the V3 loop of HIV-1 gp120 induces cross-clade neutralizing
por: Zolla-Pazner, Susan, et al.
Publicado: (2006) -
P19-21. Sequence variability in the crown of the V3 loop of the HIV-1 envelope is clustered within a small 3D structural zone
por: Almond, D, et al.
Publicado: (2009) -
P20-09. Worldwide epitope prevalence of crystallographically resolved anti-V3 antibodies
por: Swetnam, J, et al.
Publicado: (2009) -
Computational Prediction of Neutralization Epitopes Targeted by Human Anti-V3 HIV Monoclonal Antibodies
por: Shmelkov, Evgeny, et al.
Publicado: (2014)