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The Modulation of PPARγ1 and PPARγ2 mRNA Expression by Ciglitazone in CD3/CD28-Activated Naïve and Memory CD4+ T Cells

Given their roles in immune regulation, the expression of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) 1 and 2 isoforms was investigated in human naïve (CD45RA+) and memory (CD45RO+) CD4+ T cells. Stimulation of both types of cells via the CD3/CD28 pathway resulted in hi...

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Detalles Bibliográficos
Autores principales: Norazmi, Mohd Nor, Mohamed, Rafeezul, Nurul, Asma Abdullah, Yaacob, Nik Soriani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323850/
https://www.ncbi.nlm.nih.gov/pubmed/22548115
http://dx.doi.org/10.1155/2012/849195