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Divergent Roles of p75(NTR) and Trk Receptors in BDNF's Effects on Dendritic Spine Density and Morphology
Activation of TrkB receptors by brain-derived neurotrophic factor (BDNF) followed by MAPK/ERK signaling increases dendritic spine density and the proportion of mature spines in hippocampal CA1 pyramidal neurons. Considering the opposing actions of p75(NTR) and Trk receptors in several BDNF actions o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323862/ https://www.ncbi.nlm.nih.gov/pubmed/22548193 http://dx.doi.org/10.1155/2012/578057 |