Cargando…

Divergent Roles of p75(NTR) and Trk Receptors in BDNF's Effects on Dendritic Spine Density and Morphology

Activation of TrkB receptors by brain-derived neurotrophic factor (BDNF) followed by MAPK/ERK signaling increases dendritic spine density and the proportion of mature spines in hippocampal CA1 pyramidal neurons. Considering the opposing actions of p75(NTR) and Trk receptors in several BDNF actions o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chapleau, Christopher A., Pozzo-Miller, Lucas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323862/ https://www.ncbi.nlm.nih.gov/pubmed/22548193 http://dx.doi.org/10.1155/2012/578057

Ejemplares similares

Changes in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence
por: Xu, R., et al.
Publicado: (2015)

BDNF-TrkB/proBDNF-p75(NTR) pathway regulation by lipid emulsion rescues bupivacaine-induced central neurotoxicity in rats
por: Jia, Danting, et al.
Publicado: (2023)

Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism
por: Chapleau, Christopher A., et al.
Publicado: (2009)

Expression of NGF/proNGF and Their Receptors TrkA, p75(NTR) and Sortilin in Melanoma
por: Marsland, Mark, et al.
Publicado: (2022)

QS8: The Roles of the TrkA and p75NTR NGF Receptors in Corneal Wound Healing
por: Tajdaran, Kiana, et al.
Publicado: (2021)

Molecular Mechanism of Switching of TrkA/p75(NTR) Signaling in Monocrotophos Induced Neurotoxicity
por: Kumar, Vivek, et al.
Publicado: (2015)

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells
por: Bandoła, Joanna, et al.
Publicado: (2017)

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies
por: Brito, V, et al.
Publicado: (2013)

Characterization of NGF, trkA(NGFR), and p75(NTR) in Retina of Mice Lacking Reelin Glycoprotein
por: Balzamino, Bijorn Omar, et al.
Publicado: (2014)

Spatio-temporal expression profile of NGF and the two-receptor system, TrkA and p75NTR, in experimental autoimmune encephalomyelitis
por: Delivanoglou, Nickoleta, et al.
Publicado: (2020)

Tissue-Specificity of Antibodies Raised Against TrkB and p75(NTR) Receptors; Implications for Platelets as Models of Neurodegenerative Diseases
por: Fleury, Samuel, et al.
Publicado: (2021)

TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal
por: Majdan, Marta, et al.
Publicado: (2001)

Expression of Nerve Growth Factor (NGF), TrkA, and p75(NTR) in Developing Human Fetal Teeth
por: Mitsiadis, Thimios A., et al.
Publicado: (2016)

Author Correction: Molecular Mechanism of Switching of TrkA/p75(NTR) Signaling in Monocrotophos Induced Neurotoxicity
por: Kumar, Vivek, et al.
Publicado: (2020)

Effects of pre- and postnatal deletion of the transcription factor NKx2-1 on the expression of NGF, trkA, trkB and p75NTR in mice
por: Ersözlü, S, et al.
Publicado: (2015)

Deletion of p75(NTR) prevents vaso-obliteration and retinal neovascularization via activation of Trk- A receptor in ischemic retinopathy model
por: Elshaer, Sally L., et al.
Publicado: (2018)

ProBDNF/p75NTR/sortilin pathway is activated in peripheral blood of patients with alcohol dependence
por: Zhou, Li, et al.
Publicado: (2018)

Involvement of TrkB- and p75(NTR)-signaling pathways in two contrasting forms of long-lasting synaptic plasticity
por: Sakuragi, Shigeo, et al.
Publicado: (2013)

Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons
por: Ka, Minhan, et al.
Publicado: (2016)

Cdk5 Is Essential for Amphetamine to Increase Dendritic Spine Density in Hippocampal Pyramidal Neurons
por: Ferreras, Soledad, et al.
Publicado: (2017)

Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats
por: Fortress, Ashley M., et al.
Publicado: (2011)

Dendritic spine dysgenesis in Rett syndrome
por: Xu, Xin, et al.
Publicado: (2014)

Up-regulation of proBDNF/p75(NTR) signaling in antibody-secreting cells drives systemic lupus erythematosus
por: Shen, Wei-Yun, et al.
Publicado: (2022)

Up-Regulation of ProBDNF/p75(NTR) Signaling in Spinal Cord Drives Inflammatory Pain in Male Rats
por: Li, Hui, et al.
Publicado: (2023)

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin
por: Arnold, Miranda, et al.
Publicado: (2016)

Glucose homeostasis and p75(NTR): The sweet side of neurotrophin receptor signaling
por: Baeza-Raja, Bernat, et al.
Publicado: (2012)

Maternal Subclinical Hypothyroidism in Rats Impairs Spatial Learning and Memory in Offspring by Disrupting Balance of the TrkA/p75(NTR) Signal Pathway
por: Zhang, Fan, et al.
Publicado: (2021)

Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling
por: Garad, Machhindra, et al.
Publicado: (2021)

p75NTR/proBDNF Modulates Basal Cell Carcinoma (BCC) Immune Microenvironment via Necroptosis Signaling Pathway
por: Lu, Qingli, et al.
Publicado: (2021)

The role and potential mechanism of p75NTR in mineralization via in vivo p75NTR knockout mice and in vitro ectomesenchymal stem cells
por: Zhao, Manzhu, et al.
Publicado: (2020)

Hippocampal CA1 Pyramidal Neurons of Mecp2 Mutant Mice Show a Dendritic Spine Phenotype Only in the Presymptomatic Stage
por: Chapleau, Christopher A., et al.
Publicado: (2012)

NGF Modulates trkA(NGFR)/p75(NTR) in αSMA-Expressing Conjunctival Fibroblasts from Human Ocular Cicatricial Pemphigoid (OCP)
por: Micera, Alessandra, et al.
Publicado: (2015)

Pro-BDNF Contributes to Hypoxia/Reoxygenation Injury in Myocardial Microvascular Endothelial Cells: Roles of Receptors p75(NTR) and Sortilin and Activation of JNK and Caspase 3
por: Yu, Fei, et al.
Publicado: (2018)

BDNF signaling during the lifetime of dendritic spines
por: Zagrebelsky, Marta, et al.
Publicado: (2020)

p75(NTR) in Huntington's disease: beyond the basal ganglia
por: Brito, Verónica, et al.
Publicado: (2015)

(−)-Epigallocatechin-3-Gallate Ameliorates Learning and Memory Deficits by Adjusting the Balance of TrkA/p75(NTR) Signaling in APP/PS1 Transgenic Mice
por: Liu, Mingyan, et al.
Publicado: (2013)

BDNF receptor TrkB as the mediator of the antidepressant drug action
por: Casarotto, Plinio, et al.
Publicado: (2022)

Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells
por: Pham, Dan Duc, et al.
Publicado: (2019)

Reduced Anxiety-Like Behavior and Altered Hippocampal Morphology in Female p75NTR(exon IV−/−) Mice
por: Puschban, Zoe, et al.
Publicado: (2016)

Structural Characterization of the Self-Association of the Death Domain of p75(NTR)
por: Qu, Qianhui, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7jtcrh591dspksgrl4l6aov45k