Cargando…

The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are comprised of different combinations of GluA1–GluA4 (also known asGluR1–GluR4 and GluR-A to GluR-D) subunits. The GluA2 subunit is subject to RNA editing by the ADAR2 enzyme, which converts a codon for glutamine (Gln; Q), prese...

Descripción completa

Detalles Bibliográficos
Autores principales: Wright, Amanda, Vissel, Bryce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324117/
https://www.ncbi.nlm.nih.gov/pubmed/22514516
http://dx.doi.org/10.3389/fnmol.2012.00034