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Novel BRAF Alteration in a Sporadic Pilocytic Astrocytoma

Pilocytic astrocytoma (PA) is the most frequently encountered glial tumor (glioma or astrocytoma) in children. Recent studies have identified alterations in the BRAF serine/threonine kinase gene as the likely causative mutation in these childhood brain tumors. The majority of these genetic changes i...

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Detalles Bibliográficos
Autores principales: Dahiya, Sonika, Yu, Jinsheng, Kaul, Aparna, Leonard, Jeffrey R., Gutmann, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324141/
https://www.ncbi.nlm.nih.gov/pubmed/22548077
http://dx.doi.org/10.1155/2012/418672