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High expression of p16(INK4a) and low expression of Bmi1 are associated with endothelial cellular senescence in the human cornea

PURPOSE: Determine cyclin-dependent kinase inhibitor 2A (p16(Ink4a)) and polycomb ring finger oncogene (Bmi1) expression in corneal endothelium samples from different age groups and test whether the expression of p16(INK4a) and Bmi1 are associated with endothelial cellular senescence in human cornea...

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Detalles Bibliográficos
Autores principales: Wang, Ye, Zang, Xinjie, Wang, Yao, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324359/
https://www.ncbi.nlm.nih.gov/pubmed/22509111