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NGF promotes cell cycle progression by regulating D-type cyclins via PI3K/Akt and MAPK/Erk activation in human corneal epithelial cells

PURPOSE: Nerve growth factor (NGF) plays an important role in promoting the healing of corneal wounds. However, the molecular mechanism by which NGF functions is unknown. We investigated the possible effects of NGF on phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) and mitogen activated...

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Detalles Bibliográficos
Autores principales: Hong, Jiaxu, Qian, Tingting, Le, Qihua, Sun, Xinghuai, Wu, Jihong, Chen, Junyi, Yu, Xiaobo, Xu, Jianjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324366/
https://www.ncbi.nlm.nih.gov/pubmed/22509106