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Aurora kinase-C-T191D is constitutively active mutant

BACKGROUND: Aurora kinases (Aurora-A, B and C) belong to a family of conserved serine/threonine kinases which are key regulators of cell cycle progression. Aurora-A and Aurora-B are expressed in somatic cells and involved in cell cycle regulation while aurora-C is meiotic chromosome passenger protei...

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Detalles Bibliográficos
Autores principales: Khan, Jabbar, Khan, Sanaullah, Attaullah, Sobia, Ali, Ijaz, Khan, Shahid Niaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324370/
https://www.ncbi.nlm.nih.gov/pubmed/22443468
http://dx.doi.org/10.1186/1471-2121-13-8