Developing a powerful In Silico tool for the discovery of novel caspase-3 substrates: a preliminary screening of the human proteome

BACKGROUND: Caspases are a family of cysteinyl proteases that regulate apoptosis and other biological processes. Caspase-3 is considered the central executioner member of this family with a wide range of substrates. Identification of caspase-3 cellular targets is crucial to gain further insights int...

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Detalles Bibliográficos
Autores principales: Ayyash, Muneef, Tamimi, Hashem, Ashhab, Yaqoub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324375/
https://www.ncbi.nlm.nih.gov/pubmed/22269041
http://dx.doi.org/10.1186/1471-2105-13-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324375/
https://www.ncbi.nlm.nih.gov/pubmed/22269041
http://dx.doi.org/10.1186/1471-2105-13-14

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