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High recovery of cell-free methylated DNA based on a rapid bisulfite-treatment protocol
BACKGROUND: Detection of cell-free methylated DNA in plasma is a promising tool for tumour diagnosis and monitoring. Due to the very low amounts of cell-free DNA in plasma, analytical sensitivity is of utmost importance. The vast majority of currently available methods for analysing DNA methylation...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324385/ https://www.ncbi.nlm.nih.gov/pubmed/22448717 http://dx.doi.org/10.1186/1471-2199-13-12 |