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High recovery of cell-free methylated DNA based on a rapid bisulfite-treatment protocol

BACKGROUND: Detection of cell-free methylated DNA in plasma is a promising tool for tumour diagnosis and monitoring. Due to the very low amounts of cell-free DNA in plasma, analytical sensitivity is of utmost importance. The vast majority of currently available methods for analysing DNA methylation...

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Detalles Bibliográficos
Autores principales: Pedersen, Inge Søkilde, Krarup, Henrik Bygum, Thorlacius-Ussing, Ole, Madsen, Poul Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324385/
https://www.ncbi.nlm.nih.gov/pubmed/22448717
http://dx.doi.org/10.1186/1471-2199-13-12