Pdx1 Is Post-Translationally Modified In vivo and Serine 61 Is the Principal Site of Phosphorylation

Maintaining sufficient levels of Pdx1 activity is a prerequisite for proper regulation of blood glucose homeostasis and beta cell function. Mice that are haploinsufficient for Pdx1 display impaired glucose tolerance and lack the ability to increase beta cell mass in response to decreased insulin sig...

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Detalles Bibliográficos
Autores principales: Frogne, Thomas, Sylvestersen, Kathrine Beck, Kubicek, Stefan, Nielsen, Michael Lund, Hecksher-Sørensen, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324462/
https://www.ncbi.nlm.nih.gov/pubmed/22509401
http://dx.doi.org/10.1371/journal.pone.0035233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324462/
https://www.ncbi.nlm.nih.gov/pubmed/22509401
http://dx.doi.org/10.1371/journal.pone.0035233

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