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HLA-DRB1-DQB1 Haplotypes Confer Susceptibility and Resistance to Multiple Sclerosis in Sardinia

INTRODUCTION: Genetic predisposition to multiple sclerosis (MS) in Sardinia (Italy) has been associated with five DRB1*-DQB1* haplotypes of the human leukocyte antigen (HLA). Given the complexity of these associations, an in-depth re-analysis was performed with the specific aims of confirming the ha...

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Detalles Bibliográficos
Autores principales: Cocco, Eleonora, Sardu, Claudia, Pieroni, Enrico, Valentini, Maria, Murru, Raffaele, Costa, Gianna, Tranquilli, Stefania, Frau, Jessica, Coghe, Giancarlo, Carboni, Nicola, Floris, Matteo, Contu, Paolo, Marrosu, Maria Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324467/
https://www.ncbi.nlm.nih.gov/pubmed/22509268
http://dx.doi.org/10.1371/journal.pone.0033972