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Preparation and Characterization of the Extracellular Domain of Human Sid-1

In C. elegans, the cell surface protein Sid-1 imports extracellular dsRNA into the cytosol of most non-neuronal cells, enabling systemic spread of RNA interference (RNAi) throughout the worm. Sid-1 homologs are found in many other animals, although for most a function for the protein has not yet bee...

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Detalles Bibliográficos
Autores principales: Pratt, Ashley J., Rambo, Robert P., Lau, Pick-Wei, MacRae, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324469/
https://www.ncbi.nlm.nih.gov/pubmed/22509261
http://dx.doi.org/10.1371/journal.pone.0033607