Epigenetic Factors in Cancer Risk: Effect of Chemical Carcinogens on Global DNA Methylation Pattern in Human TK6 Cells

In the current study, we assessed the global DNA methylation changes in human lymphoblastoid (TK6) cells in vitro in response to 5 direct and 10 indirect-acting genotoxic agents. TK6 cells were exposed to the selected agents for 24 h in the presence and/or absence of S9 metabolic mix. Liquid chromat...

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Detalles Bibliográficos
Autores principales: Tabish, Ali M., Poels, Katrien, Hoet, Peter, Godderis, Lode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324488/
https://www.ncbi.nlm.nih.gov/pubmed/22509344
http://dx.doi.org/10.1371/journal.pone.0034674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324488/
https://www.ncbi.nlm.nih.gov/pubmed/22509344
http://dx.doi.org/10.1371/journal.pone.0034674

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