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Modulators of Prostate Cancer Cell Proliferation and Viability Identified by Short-Hairpin RNA Library Screening

There is significant need to identify novel prostate cancer drug targets because current hormone therapies eventually fail, leading to a drug-resistant and fatal disease termed castration-resistant prostate cancer. To functionally identify genes that, when silenced, decrease prostate cancer cell pro...

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Detalles Bibliográficos
Autores principales: Dahlman, Kimberly Brown, Parker, Joel S., Shamu, Tambudzai, Hieronymus, Haley, Chapinski, Caren, Carver, Brett, Chang, Kenneth, Hannon, Gregory J., Sawyers, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324507/
https://www.ncbi.nlm.nih.gov/pubmed/22509301
http://dx.doi.org/10.1371/journal.pone.0034414