Miz1 Is a Critical Repressor of cdkn1a during Skin Tumorigenesis

The transcription factor Miz1 forms repressive DNA-binding complexes with the Myc, Gfi-1 and Bcl-6 oncoproteins. Known target genes of these complexes encode the cyclin-dependent kinase inhibitors (CKIs) cdkn2b (p15(Ink4)), cdkn1a (p21(Cip1)), and cdkn1c (p57(Kip2)). Whether Miz1-mediated repression...

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Detalles Bibliográficos
Autores principales: Hönnemann, Jan, Sanz-Moreno, Adrián, Wolf, Elmar, Eilers, Martin, Elsässer, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324535/
https://www.ncbi.nlm.nih.gov/pubmed/22509363
http://dx.doi.org/10.1371/journal.pone.0034885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324535/
https://www.ncbi.nlm.nih.gov/pubmed/22509363
http://dx.doi.org/10.1371/journal.pone.0034885

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