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The proteomes of transcription factories containing RNA polymerases I, II or III

Human nuclei contain three RNA polymerases (I, II, and III) that transcribe different groups of genes; the active forms of all three are difficult to isolate because they are bound to the substructure. Here, we describe a purification approach for isolating active RNA polymerase complexes from mamma...

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Detalles Bibliográficos
Autores principales: Melnik, Svitlana, Deng, Binwei, Papantonis, Argyris, Baboo, Sabyasachi, Carr, Ian M., Cook, Peter R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324775/
https://www.ncbi.nlm.nih.gov/pubmed/21946667
http://dx.doi.org/10.1038/nmeth.1705