Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or in combination with ionizing radiation were studied with MCF-7 human breast cancer cells and FSaII mouse fibrosarcoma cells. Clinically achievable concentrations of metformin caused significant clonogenic d...

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Detalles Bibliográficos
Autores principales: Song, Chang W., Lee, Hyemi, Dings, Ruud P. M., Williams, Brent, Powers, John, Santos, Troy Dos, Choi, Bo-Hwa, Park, Heon Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324825/
https://www.ncbi.nlm.nih.gov/pubmed/22500211
http://dx.doi.org/10.1038/srep00362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324825/
https://www.ncbi.nlm.nih.gov/pubmed/22500211
http://dx.doi.org/10.1038/srep00362

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