Cargando…

Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or in combination with ionizing radiation were studied with MCF-7 human breast cancer cells and FSaII mouse fibrosarcoma cells. Clinically achievable concentrations of metformin caused significant clonogenic d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Chang W., Lee, Hyemi, Dings, Ruud P. M., Williams, Brent, Powers, John, Santos, Troy Dos, Choi, Bo-Hwa, Park, Heon Joo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324825/ https://www.ncbi.nlm.nih.gov/pubmed/22500211 http://dx.doi.org/10.1038/srep00362

Ejemplares similares

Syrosingopine sensitizes cancer cells to killing by metformin
por: Benjamin, Don, et al.
Publicado: (2016)

Response of Breast Cancer Cells and Cancer Stem Cells to Metformin and Hyperthermia Alone or Combined
por: Lee, Hyemi, et al.
Publicado: (2014)

Preferential killing of multidrug-resistant KB cells by inhibitors of glucosylceramide synthase
por: Nicholson, K M, et al.
Publicado: (1999)

Preferential killing of melanoma cells by a p16-related peptide
por: Soo, Julia K., et al.
Publicado: (2023)

Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2
por: Lv, Hongwei, et al.
Publicado: (2018)

Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation
por: Li, Guan-Nan, et al.
Publicado: (2022)

CD56(bright) natural killer cells preferentially kill proliferating CD4(+) T cells
por: Lee, Mercede, et al.
Publicado: (2023)

Preferential killing of human lung cancer cell lines with mitochondrial dysfunction by nonthermal dielectric barrier discharge plasma
por: Panngom, K, et al.
Publicado: (2013)

Antibiotic in myrrh from Commiphora molmol preferentially kills nongrowing bacteria
por: Bhattacharjee, Mrinal K, et al.
Publicado: (2020)

Targeting the Checkpoint to Kill Cancer Cells
por: Benada, Jan, et al.
Publicado: (2015)

Polydopamine nanoparticles kill cancer cells
por: Nieto, Celia, et al.
Publicado: (2018)

Triple-negative breast cancer targeting and killing by EpCAM-directed, plasmonically active nanodrug systems
por: Jenkins, Samir V., et al.
Publicado: (2017)

Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells
por: Yi, Lan, et al.
Publicado: (2014)

Non-coding rRNA-mediated preferential killing in cancer cells is enhanced by suppression of autophagy in non-transformed counterpart
por: Hwang, C J, et al.
Publicado: (2011)

Metformin-induced preferential killing of breast cancer initiating CD44(+)CD24(−/low) cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts
por: Cufí, Sílvia, et al.
Publicado: (2012)

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells
por: Sánchez-Martínez, Diego, et al.
Publicado: (2016)

CRISPR-to-Kill (C2K)–Employing the Bacterial Immune System to Kill Cancer Cells
por: Głów, Dawid, et al.
Publicado: (2021)

Male Killing Spiroplasma Preferentially Disrupts Neural Development in the Drosophila melanogaster Embryo
por: Martin, Jennifer, et al.
Publicado: (2013)

Killing controversy
por: Williams, Ruth
Publicado: (2006)

Oxidizing to death: Disulfiram for cancer cell killing
por: Brüning, Ansgar, et al.
Publicado: (2014)

How Taxol/paclitaxel kills cancer cells
por: Weaver, Beth A.
Publicado: (2014)

Synergy of BID with doxorubicin in the killing of cancer cells
por: ORZECHOWSKA, EMILIA JOANNA, et al.
Publicado: (2015)

Kinetic Heterogeneity of Cancer Cell Fractional Killing
por: Inde, Zintis, et al.
Publicado: (2020)

Tetrandrine, a Compound Common in Chinese Traditional Medicine, Preferentially Kills Breast Cancer Tumor Initiating Cells (TICs) In Vitro
por: Xu, Wei, et al.
Publicado: (2011)

An Aqueous Extract of Marine Microalgae Exhibits Antimetastatic Activity through Preferential Killing of Suspended Cancer Cells and Anticolony Forming Activity
por: Somasekharan, Syam Prakash, et al.
Publicado: (2016)

Killing two birds with one stone: Blocking the mitochondrial pyruvate carrier to inhibit lactate uptake by cancer cells and radiosensitize tumors
por: Linden, Catherine Vander, et al.
Publicado: (2018)

Cancer cells can be killed mechanically or with combinations of cytoskeletal inhibitors
por: Tijore, Ajay, et al.
Publicado: (2022)

The transformation of targeted killing and international order
por: Senn, Martin, et al.
Publicado: (2017)

Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC
por: Gilormini, Marion, et al.
Publicado: (2016)

Kill the Cancer Save the Eggs
por: Susman, E
Publicado: (2003)

Cancer kill code extension
por: Peter, Marcus E.
Publicado: (2023)

Modeling long-term tumor growth and kill after combinations of radiation and radiosensitizing agents
por: Cardilin, Tim, et al.
Publicado: (2019)

2-Deoxy-D-glucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis.
por: Bell, S. E., et al.
Publicado: (1998)

Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
por: Chen, Yong, et al.
Publicado: (2015)

Selective cancer cell killing by α-tocopheryl succinate
por: Neuzil, J, et al.
Publicado: (2001)

Liprotides kill cancer cells by disrupting the plasma membrane
por: Frislev, Henriette S., et al.
Publicado: (2017)

Selective killing of cancer cells by nanoparticle-assisted ultrasound
por: Kosheleva, Olga K., et al.
Publicado: (2016)

Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer
por: Roh, Jong-Lyel, et al.
Publicado: (2014)

NK cells specifically TCR-dressed to kill cancer cells
por: Mensali, Nadia, et al.
Publicado: (2019)

Triple kill: DDR inhibitors, radiotherapy and immunotherapy leave cancer cells with no escape: DDR inhibitors, radiotherapy and immunotherapy can kill cancer cells
por: Qiu, Yuyue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9ikbihls1mu3fv3av7vvif6snr