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Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit
Gene expression actualizes the organismal phenotypes encoded within the genome in an environment-dependent manner. Among all encoded phenotypes, cell population growth rate (fitness) is perhaps the most important, since it determines how well-adapted a genotype is in various environments. Traditiona...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325171/ https://www.ncbi.nlm.nih.gov/pubmed/22511863 http://dx.doi.org/10.1371/journal.pcbi.1002480 |