Cargando…
Mapping the Environmental Fitness Landscape of a Synthetic Gene Circuit
Gene expression actualizes the organismal phenotypes encoded within the genome in an environment-dependent manner. Among all encoded phenotypes, cell population growth rate (fitness) is perhaps the most important, since it determines how well-adapted a genotype is in various environments. Traditiona...
Autores principales: | Nevozhay, Dmitry, Adams, Rhys M., Van Itallie, Elizabeth, Bennett, Matthew R., Balázsi, Gábor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325171/ https://www.ncbi.nlm.nih.gov/pubmed/22511863 http://dx.doi.org/10.1371/journal.pcbi.1002480 |
Ejemplares similares
-
Transferring a synthetic gene circuit from yeast to mammalian cells
por: Nevozhay, Dmitry, et al.
Publicado: (2013) -
Multiplexed Gene Expression Tuning with Orthogonal
Synthetic Gene Circuits
por: Szenk, Mariola, et al.
Publicado: (2020) -
Tuning and controlling gene expression noise in synthetic gene networks
por: Murphy, Kevin F., et al.
Publicado: (2010) -
Stress-response balance drives the evolution of a network module and its host genome
por: González, Caleb, et al.
Publicado: (2015) -
Mapping the operational landscape of microRNAs in synthetic gene circuits
por: Quarton, Tyler, et al.
Publicado: (2018)