Whole-Exome Sequencing and Homozygosity Analysis Implicate Depolarization-Regulated Neuronal Genes in Autism

Although autism has a clear genetic component, the high genetic heterogeneity of the disorder has been a challenge for the identification of causative genes. We used homozygosity analysis to identify probands from nonconsanguineous families that showed evidence of distant shared ancestry, suggesting...

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Detalles Bibliográficos
Autores principales: Chahrour, Maria H., Yu, Timothy W., Lim, Elaine T., Ataman, Bulent, Coulter, Michael E., Hill, R. Sean, Stevens, Christine R., Schubert, Christian R., Greenberg, Michael E., Gabriel, Stacey B., Walsh, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325173/
https://www.ncbi.nlm.nih.gov/pubmed/22511880
http://dx.doi.org/10.1371/journal.pgen.1002635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325173/
https://www.ncbi.nlm.nih.gov/pubmed/22511880
http://dx.doi.org/10.1371/journal.pgen.1002635

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